Rupture risk assessment for intracranial aneurysms

Intracranial aneurysms, which are dilatations of the cerebral vasculature, can be prone to rupture. To assess the patient-specific rupture risk, hemodynamic parameters are acquired using Computational Fluid Dynamics (CFD). However, the impact of the vessel wall is mostly neglected. To overcome this limitation, precise vessel wall imaging was performed in a 33-year old male human, who died due to aneurysm rupture. Furthermore, fluid-structure interaction (FSI) simulations were carried out considering patient-specific and constant vessel wall thickness, respectively. Although the hemodynamic variables (e.g. wall shear stress) do not vary significantly after the FSI computations, the importance of occurring wall stresses is shown. Especially, the comparison between individual and constant vessel wall demonstrates that significantly different stress distributions are predicted, particularly close to the actual rupture site. Overall, the study highlights that the consideration of wall information is a crucial step towards the assessment of an individual rupture risk for cerebral aneurysms. Hence, CFD might become a valuable supporting tool for physicians during therapy planning in the future.

Presenter(s): 
University of Magdeburg
Samuel Voß
Session Time Slot(s): 
Time: 
07/03/2017 - 9:45am-07/03/2017 - 10:10am
Room: 
Room I
Presentation Image: 
Session Track: 

Session Tracks (STAR Global Conference 2017)

Co-Author(s): 
First Name: 
Philipp
Last Name: 
Berg
Company / Institution: 
Department of Fluid Dynamics & Technical Flows, University of Magdeburg, Germany
First Name: 
Sylvia
Last Name: 
Saalfeld
Company / Institution: 
Department of Simulation and Graphics, University of Magdeburg, Germany
First Name: 
Thomas
Last Name: 
Hoffmann
Company / Institution: 
Institute of Neuroradiology, University Hospital Magdeburg, Germany
First Name: 
Oliver
Last Name: 
Beuing
Company / Institution: 
Institute of Neuroradiology, University Hospital Magdeburg, Germany
First Name: 
Gábor
Last Name: 
Janiga
Company / Institution: 
Department of Fluid Dynamics & Technical Flows, University of Magdeburg, Germany
First Name: 
Dominique
Last Name: 
Thévenin
Company / Institution: 
Department of Fluid Dynamics & Technical Flows, University of Magdeburg, Germany